AIDS drugs in combination Qiaozhi
A new study shows that those with anti-retroviral therapy has no effect of HIV infection, the future combination of amino acids with a drug treatment, may be able to significantly improve their existence.
Imperial College London researchers at institutions such as 1, in the “Journal of Immunology” says, they called D-1mT amino acid drugs and combination antiretroviral therapy, significantly reduces the body’s simian immunodeficiency monkey SIV virus levels.SIV is by far the closest known human HIV virus.
At present, the treatment of AIDS is commonly used highly active antiretroviral therapy, commonly known as cocktail therapy, but about one in ten HIV-infected persons because of drug resistance and other factors, efficacy of this treatment would not help them.Therefore, the researchers hope their new study in the future can improve the efficacy of cocktails.
Chinese researchers have used in the experiment 11 monkeys infected with SIV, they will receive training in cocktail therapy, treatment for at least 4 months, the results of which only three of the SIV in vivo reduced the level of unpredictable, and the other eight were not seen effective, SIV is still maintain a high level.
The researchers then let the eight monkeys daily doses of D-1mT, and at the 6th day and 13th day, blood test and found that the first 6 days only three macaques SIV in vivo levels are still detectable level, the first 13 days there are only two monkeys in vivo can be measured at the level of SIV levels, and the content is very low.
In addition, animal experiments also confirmed that only the D-1mT treatment of monkeys infected with SIV, and no therapeutic benefit.The researchers said the next step that they will study how to play D-1mT efficacy.
At present, some research groups are conducting initial clinical trials validate D-1mT the treatment of cancer of the safety and efficacy.The researchers pointed out that if tests prove that D-1mT can safely apply the human body, is expected to be five years, they first began to implement the D-1mT a cure for AIDS clinical trials.
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